Jul 25, 2025
Accelerated Symptom Reduction in Severe OCD with Anodal tDCS + CET
Learn how EASE treated Persistent obsessive–compulsive symptoms with marked distress, functional interference, and desire for faster symptom reduction

EASE Case Study
Content Designer

Patient Identification: Rohan (pseudonym), 21-year-old male
Clinical Status: Long-standing Obsessive Compulsive Disorder (OCD 2–3 years), presenting with intrusive thoughts and repetitive compulsive behaviors. No significant comorbid psychiatric conditions reported.
Primary Complaint: Persistent obsessive–compulsive symptoms with marked distress, functional interference, and desire for faster symptom reduction
Diagnosis: Obsessive Compulsive Disorder (F42)
Baseline Status: Moderate–severe compulsions with partial response to medication
Additional Context: The patient had been on stable psychiatric medications for more than 2–3 years before initiation of neuromodulation. Although improving, he sought accelerated recovery and reduction of compulsive rituals.
Intervention
Treatment Modality: Active anodal tDCS administered through the Ease device, paired with Cognitive Emotional Training (CET) modules.
Protocol Parameters:
Electrode Montage: Anode – Left DLPFC (F3); Cathode – Right DLPFC (F4)
Current Intensity: 2 mA
Session Duration: 20 minutes
Total Sessions: 50 sessions (initial 30-session package extended based on clinical response)
Frequency: Once daily (modified from the standard twice-daily protocol due to feasibility)
Maintenance: Continues weekly booster sessions
Cognitive Emotional Training Components:
Emotional N-Back Task: targeting affective working memory
Flanker Task: improving cognitive control and interference resolution
Corsi Block Task: enhancing visuospatial working memory
Go/No-Go Task: strengthening response inhibition
Each CET task was delivered with adaptive difficulty based on accuracy, ensuring sustained engagement and progressive activation of cognitive–emotional regulatory circuits.
Rationale for tDCS addition: The objective was to reduce compulsions faster.
Outcome Measures
Symptom severity was evaluated pre- and post-treatment using validated clinician-rated scales:
Clinical-rated improvements in compulsive frequency and severity
Patient self-reports regarding intrusive thoughts, compulsive urges, distress and functional capacity
Longitudinal observations during booster sessions.
Results
After 50 sessions, the patient demonstrated marked clinical improvement ( > 60%).
Symptom change
Domain | Baseline | Post-intervention | % Change |
Compulsion | Moderate-severe | Mild | ≈80% reduction (self-reported) |
Functional Impairment | High | Minimal | Significant Improvement |
Clinical Observations
Major reduction in compulsive frequency and urgency
Improved cognitive control over intrusive thoughts
Enhanced daily functioning and emotional stability
Greater confidence and autonomy in managing OCD triggers
No adverse effects were reported; sessions were well tolerated.
“Working on this case taught me the compounding effects of neuromodulation & the importance of consistency. ”
Dr. Pooja Dubey




